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Information about Cardizem.

You should not use this medication if you are allergic to diltiazemor if you have:

Do not give these medicines to anyone elseeven if cheap cardizem sr have the same condition cheap cardizem sr you.

This medication should be used only when clearly needed during pregnancyDiscuss the risks and benefits with your doctor.

All medicines have risks and benefitsYour doctor has weighed the risks of you taking these medicines against the benefits they expect it will have for you.

Your doctor and pharmacist may have more information on medicines to be careful with or to avoid while taking Cardizem CD capsules or Cardizem tablets.

The following postmarketing events have been reported infrequently in patients receiving CARDIZEMacute generalized exanthematous pustulosisallergic reactionsalopeciaangioedemaincluding facial or periorbital edemaasystoleerythema multiformeincluding Stevens-Johnson syndrometoxic epidermal necrolysisextrapyramidal symptomsgingival hyperplasiahemolytic anemiaincreased bleeding timeleukopeniaphotosensitivityincluding lichenoid keratosis and hyperpigmentation at sun-exposed skin areaspurpuraretinopathymyopathyand thrombocytopeniaThere have been observed cases of a generalized rashsome characterized as leukocytoclastic vasculitisIn additionevents such as myocardial infarction have been observedwhich are not readily distinguishable from the natural history of the disease in these patientsA definitive cause and effect relationship between these events and CARDIZEM therapy cannot yet be establishedExfoliative dermatitisproven by cheap cardizem sr also been reported.

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The toxic dose in man is not knownDue to extensive metabolismblood levels after cheap cardizem sr standard dose of diltiazem can vary over tenfoldlimiting the usefulness of blood levels in overdose cases.

Diltiazem is an inhibitor of CYP3A4 and cheap cardizem sr been shown to increase significantly the AUC of some statinsThe risk of myopathy and rhabdomyolysis with statins metabolized by CYP3A4 may be increased with concomitant use of diltiazemWhen possibleuse a non-CYP3A4-metabolized statin together with cheap cardizem sr adjustments for both diltiazem and the statin should be considered along with close monitoring for signs and symptoms of any statin related adverse events.

This list is not complete and other drugs may interact with diltiazemTell your doctor about all medications you useThis includes prescriptionover-cheap cardizem sr-countervitaminand herbal productsDo not start a new medication without telling your doctor.

In mandiltiazem prevents spontaneous and ergonovine-provoked coronary artery spasmIt causes a decrease in peripheral vascular resistance and a modest fall in blood pressureand in exercise tolerance studies in patients with ischemic heart diseasereduces the heart rate-blood pressure product for any given workloadStudies to dateprimarily in patients with good ventricular functionhave not revealed evidence of a negative inotropic effectcardiac outputejection fractionand left ventricular end-diastolic pressure have not been affectedThere are as yet few data on the interaction of diltiazem and beta-blockersResting heart rate is usually unchanged or slightly reduced by diltiazem.

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These medicines belong to a group of medicines called calcium channel blockers or calcium antagonistsThey work by opening up blood vesselswhich lowers blood pressure and lets more blood and oxygen reach the heartThey do not change the amount of calcium in your blood or bones.

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many nurses are apprehensive about having to titrate a cardizem drip.

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